Ok, I know this is the "age old" debate, but this is not about me..lol I took an x-gf shooting today. She has been thinking about getting a gun for home defense and we are talking about that.. anyway.... I rented a sig .40, sig .22, breatta 9mm, and had my kimber. She liked the .22 the most and was more accuarte with it and she said "it did not scare her as much." lol Anyway, I did my best to offer my opinion and what LITTLE I know about guns and I *think* a .22 is too small of a caliber ( I did not say this hence why I am here..lol ) , she feels comfortable with it and can shoot it and load it without any problems. So to the question and to get more insight, is a .22 a good home defense round? I know I have read if you are comfortable with the gun and can shoot it, then it will work for you. But, will a .22 handgun work for personal protection?